City of Hope Opens the Most Advanced Comprehensive Cancer Center in Orange County, Calif., Delivering World-Renowned Treatment, Research and Cancer Cures to the Nation’s Sixth Largest County

IRVINE — City of Hope, one of the largest cancer research and treatment organizations in the United States, opens its visionary comprehensive cancer center in Orange County, California, creating a national model for delivering breakthrough research and pioneering treatments. The academic cancer center ushers in a new era of hope for people with cancer.

City of Hope Opens the Most Advanced Comprehensive Cancer Center in Orange County. Photo by Keyang Pang
City of Hope Opens the Most Advanced Comprehensive Cancer Center in Orange County. Photo by Keyang Pang

Here, a team of some of the world’s most acclaimed physician-scientists — with expertise in lung, breast, gastrointestinal, gynecological, genitourinary, blood cancers and more — leads next-level cancer treatment and research.

City of Hope Orange County Lennar Foundation Cancer Center was made possible by a transformational $50 million gift from Lennar Foundation, the charitable arm of homebuilder Lennar Corporation. In Orange County alone, City of Hope has more than 15,000 philanthropic supporters who fuel its mission to end cancer.

City of Hope Orange County President Annette Walker. Photo by Keyang Pang

City of Hope Orange County President Annette Walker said, “With the opening of City of Hope Orange County Lennar Foundation Cancer Center, we are delivering on our promise to the people of Orange County and changing cancer care for our family, friends and neighbors. Four years ago, we pledged to bring the most advanced cancer care to Orange County, home to 3.2 million people. As we open our cancer center’s doors, our highly committed teams join the community in celebrating the delivery of tomorrow’s lifesaving treatments to those who need them today. Hope is truly here in Orange County.”

Dr. Edward Kim, physician-in-chief for City of Hope Orange County. Photo by Keyang Pang

“This extraordinary cadre of preeminent cancer physician-scientists changes the Orange County landscape. Our physician roster comprises many of the best minds in the world for preventing, treating, and curing cancer. With their highly specialized expertise, distinguished history of research breakthroughs and compassionate approach, this team will transform our ability to address cancer for generations.” said Dr. Edward Kim, physician-in-chief for City of Hope Orange County.

A Cancer Crisis in Orange County and Across the Nation

City of Hope officials cite several reasons for an expanded presence in the region.

Nearly 20% of residents with cancer have left the area for advanced care, with many heading to City of Hope’s main campus in Duarte, California — an up to two-hour commute each way. In addition, despite its reputation for healthy living, Orange County is not immune from the 1 in 3 national statistic for cancer incidence.

Percy Lee, Medical director of OC Coastal Region Radiation Oncology. Photo by Keyang Pang
Jason Salsamendi, lead Interventional Radiologist at City of Hope OC. Photo by Keyang Pang

In fact, the cancer incidence rate in the county is projected to increase by 18% over the next decade. Cancer risk increases with age and Orange County has a higher percentage of seniors than the U.S. average.

City of Hope, one of only 52 National Cancer Institute-designated comprehensive cancer centers in the county, is answering the call to extend its personalized care, outstanding research and lifesaving treatments closer to home for the county’s 3.2 million residents. City of Hope was recognized as the seventh “Best Hospital” for cancer in the nation, according to U.S. News & World Report’s 2022-23 Best Hospitals: Specialty Ranking.

City of Hope Opens the Most Advanced Comprehensive Cancer Center in Orange County. Photo by Keyang Pang
City of Hope Opens the Most Advanced Comprehensive Cancer Center in Orange County. Photo by Keyang Pang

Distinguishing clinical services at City of Hope Orange County Lennar Foundation Cancer Center will include:

  • Acclaimed cancer expertise: Access to City of Hope’s 575 physicians and more than 1,000 researchers and scientists who only focus on cancer.
  • Lifesaving clinical trials: Access to nearly 1,000 innovative Phase 1-3 clinical trials being conducted at City of Hope each year — more cancer-focused clinical trials than anywhere in the area — to provide patients with promising new treatments long before they become the standard of care.
  • Breakthrough treatments: Targeted immunotherapies, including CAR T cell therapy, as well as bone marrow transplants, robotic minimally invasive surgeries and MRI-guided radiation oncology. These innovations have demonstrated improved outcomes and a better quality of life for patients in treatment.
  • Leading-edge technology: The latest and most comprehensive suite of market-leading radiology, interventional radiology and radiation oncology equipment, providing a powerful combination of high tech and high touch.
  • Integrative medicine: A trailblazing integrative medicine program combining the best of Western medicine and evidence-based complementary therapies, such as acupuncture, massage and meditation.
  • Cancer prevention: Programs that identify people and families with elevated cancer risk utilizing genetic risk assessments, biomarker panels and environmental surveys to help manage that risk.
  • Early detection: Novel blood testing and imaging techniques that find cancer early, when it is still easily curable. Patients will be among the first in the nation to have access to City of Hope’s new Center for Cancer Prevention and Early Detection.
  • Precision medicine: Best-in-class genomic testing to profile a patient’s tumor and determine the treatment that will be most effective for their cancer.
  • Screening and diagnostic services: A suite of state-of-the-art imaging equipment and procedural suites, giving patients convenient access to mammography, colonoscopy, robotic bronchoscopy and other lifesaving services.
  • A clinical research unit: The epicenter for clinical investigational research that speeds the development of new drugs and interventions to the bedside, allowing patients to receive the latest treatments in cancer care.
  • Surgical oncology: An outpatient surgery department that offers advanced perioperative care, an endoscopy suite and operating rooms with robotic-assisted surgical capabilities.
  • Supportive care: City of Hope is a national leader in evidence-based supportive care. The Sheri & Les Biller Patient and Family Resource Center at the comprehensive cancer center in Irvine will facilitate easy access to a wide range of programs, including care navigation, survivorship programs, psychological and spiritual counseling, pain management and more.
City of Hope Opens the Most Advanced Comprehensive Cancer Center in Orange County. Photo by Keyang Pang
City of Hope Opens the Most Advanced Comprehensive Cancer Center in Orange County. Photo by Keyang Pang
Hope Boutique. Photo by Keyang Pang

Built For and With the Community 

City of Hope Orange County Lennar Foundation Cancer Center was designed with input from more than 500 patients, their families and community members. Every feature of the cancer center — from the design of its gathering spaces to its lighting, its wall color, even its artwork selection — was intentionally chosen to promote healing and comfort and ensure patients and their families have the best care experience. Every employee is committed to delivering compassionate care, continuing the City of Hope legacy of taking patients’ hands and never letting go.

Features include:

  • 67 spacious exam and treatment rooms.
  • 15 consultation rooms equipped with the latest technology, allowing patients and family members to meet comfortably with their care team.
  • An infusion center designed around patient preferences with 43 infusion bays and 10 private infusion treatment rooms. The infusion bays feature repositionable furnishings, flexible privacy options, and panoramic views of the Saddleback mountains.
  • Hope Boutique, a full-service salon and specialty shopping experience with oncology-trained cosmetologists who help patients with customized cosmetology services, breast prostheses and more.
  • A retail and specialty pharmacy that dispenses traditional, specialty, and over-the-counter medications, alleviating the travel burden on patients for their medication needs. In addition, a compounding pharmacy provides a full evaluation of patients’ needs and prepares personalized chemotherapeutic and non-chemotherapeutic medications. Specialty-trained clinical pharmacists assist patients with medication management.
  • A full range of state-of-the-art laboratory services in one location, making it convenient for patients to get routine blood draws.
  • Feng Shui design, art galleries, a healing garden, dedicated space for family members to gather or work, and programs to care for the whole patient — mind, body, and spirit.

City of Hope Orange County’s cancer care network currently includes four regional clinics — two in Newport Beach, one in Huntington Beach and one in Irvine. The cancer center, the regional clinics and the planned hospital will create Orange County’s largest network dedicated exclusively to cancer treatment and cures.

City of Hope Opens the Most Advanced Comprehensive Cancer Center in Orange County. Photo by Keyang Pang
City of Hope Opens the Most Advanced Comprehensive Cancer Center in Orange County. Photo by Keyang Pang
The Wishing Tree at City of Hope. Photo by Keyang Pang
City of Hope Opens the Most Advanced Comprehensive Cancer Center in Orange County. Photo by Keyang Pang
City of Hope Opens the Most Advanced Comprehensive Cancer Center in Orange County. Photo by Keyang Pang

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